NAD + 10 vials 500mg

What Is NAD+

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in every living cell. It shuttles electrons between metabolic reactions by cycling between its oxidized form, NAD+, and its reduced form, NADH, which places it at the center of glycolysis, the citric acid cycle, and oxidative phosphorylation.

Beyond redox chemistry, NAD+ is consumed as a substrate by sirtuins, PARP enzymes, and CD38, linking cellular energy status to gene regulation and DNA repair. Laboratories that buy NAD+ typically use it as a reference coenzyme in metabolic assays or to supply the cellular NAD+ pool directly. For background, see our complete guide to peptides.

Key Research Applications

·         Cellular Energy Metabolism: Investigated as the primary electron carrier feeding the mitochondrial electron transport chain and ATP synthesis.

·         Sirtuin Activation: Studied as the obligate substrate for the SIRT1–SIRT7 family of NAD+-dependent deacetylases that regulate metabolism and stress responses.

·         Mitochondrial Function: Explored in models of mitochondrial biogenesis, age-related metabolic decline, and nuclear-mitochondrial communication.

·         DNA Repair Signaling: Examined as the cofactor consumed by PARP1 and PARP2 during repair of single-strand DNA breaks.

Most laboratories buy NAD+ for one of these four programs, and the vial sizes are matched to them: 100 mg for assay development, 500 mg for multi-week culture series, and 1000 mg for repeated-dose or animal-model work.